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مروری بر گیاهان دارویی مورد استفاده در درمان بیماریهای تنفسی در طب سنتی ایران | ||
پژوهش های پیشرفته در گیاهان دارویی | ||
دوره 2، شماره 1 - شماره پیاپی 2، خرداد 1402، صفحه 1-16 اصل مقاله (961.99 K) | ||
نوع مقاله: مقاله مروری | ||
شناسه دیجیتال (DOI): 10.30479/armp.2023.18198.1007 | ||
نویسندگان | ||
حسن فلاح حسینی1؛ اقبال جاسمی2؛ مهدی صابری3؛ محمدرضا قلی بیکیان4؛ بهزاد فروتن* 5، 6 | ||
1دانشیار، گروه فارماکولوژی و طب کاربردی مرکز تحقیقات گیاهان دارویی، پژوهشکده گیاهان دارویی جهاد دانشگاهی، کرج | ||
2دانشجوی دکتری، گروه فارماکولوژی و طب کاربردی مرکز تحقیقات گیاهان دارویی، پژوهشکده گیاهان دارویی جهاد دانشگاهی، کرج | ||
3استادیار، گروه فارماکولوژی دانشکده داروسازی دانشگاه علوم پزشکی بقیه الله (عج)، تهران | ||
4استادیار، گروه شیمی آلی دانشکده شیمی دانشگاه کاشان، کاشان | ||
5دانشیار، مرکز تحقیقات بیماری های واگیر و گرمسیری، دانشگاه علوم پزشکی ایرانشهر، ایرانشهر | ||
6دانشیار، گروه فارماکولوژی، دانشکده پرشکی، دانشگاه علوم پزشکی ایرانشهر، ایرانشهر | ||
تاریخ دریافت: 27 آذر 1401، تاریخ بازنگری: 21 بهمن 1401، تاریخ پذیرش: 14 فروردین 1402 | ||
چکیده | ||
بهرغم پیشرفتهای گسترده در تحقیقات علوم پزشکی و دارویی، بسیاری از میکروبها و ویروسهای شایع که باعث عفونتهای سیستم تنفسی میشوند به درمانهای رایج مقاوم شدهاند. در همین راستا اثر مثبت گیاهان دارویی مورد استفاده در طب سنتی ایران در کاهش علائم و درمان عفونتهای سیستم تنفسی در حیوان و انسان گزارش شده است. در این مطالعه مروری، جستجو در پایگاههای اطلاعاتی ملی و بینالمللی با استفاده از کلید واژههایی مانند گیاهان دارویی، ضد ویروس، تعدیلکننده سیستم ایمنی، ضد التهاب، ضد میکروب، آنتی اکسیدان، تنگی نفس، خلط آور و ضد سرفه برای مطالعات منتشر شده تا سال 2022 انجام شد. نتایج نشان داد که در طب سنتی ایران پیاز عنصل، پر سیاوشان، شیرین بیان، پنیرک، سپستان، مرزنجوش، افسنطین، زوفا، پولک، بوزیدان، میخک، گندواش، خولنجان، سرخارگل و آویشن به عنوان خلط آور، بهبود تنگی نفس، ضد سرفه، ضد ویروس و تعدیلکننده سیستم ایمنی کاربرد بیشتری داشتهاند. بیشترین تحقیقات آزمایشگاهی و بالینی روی گیاه سرخارگل به عنوان تعدیلکننده سیستم ایمنی و سپس شیرین بیان به عنوان ضد ویروس انجام شده است. بیشترین فرآورده دارویی دارای مجوز فروش در بازار دارویی ایران به سرخارگل و آویشن در درمان عفونتهای تنفسی مربوط است. به نظر میرسد که گیاهان دارویی بررسی شده این توانایی را دارند که به عنوان بستر تحقیقاتی برای شناسایی گیاهان دارویی در درمان حمایتی به منظور پیشگیری و کنترل علائم ابتلا به عفونتهای تنفسی مورد بررسی قرار گیرند. | ||
کلیدواژهها | ||
تنگی نفس؛ خلط آور؛ ضد سرفه؛ ضد ویروس؛ گیاهان دارویی | ||
عنوان مقاله [English] | ||
A review of medicinal plants used in the treatment of respiratory diseases in Iranian traditional medicine | ||
نویسندگان [English] | ||
Hasan Fallah Huseini1؛ Eghbal Jasemi2؛ Mehdi Saberi3؛ Mohammadreza Gholibekian4؛ Behzad Foroutan5، 6 | ||
1Associate Professor, Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran | ||
2Ph.D Student, Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran | ||
3Assistant Professor, Dept. of Pharmacology and Toxicology and Applied Neuroscience Research Center, Baghiatollah University of Medical Sciences, Tehran, Iran | ||
4Assistant Professor, Dept. of Organic Chemistry, College of Chemistry, Kashan University, Kashan, Iran | ||
5Associate Professor, Tropical and Communicable Diseases Research Centre, Iranshahr University of Medical Sciences, Iranshahr, Iran|Associate Professor, Dept. of Pharmacology, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran | ||
6Associate Professor, Tropical and Communicable Diseases Research Centre, Iranshahr University of Medical Sciences, Iranshahr, Iran|Associate Professor, Dept. of Pharmacology, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran | ||
چکیده [English] | ||
Despite extensive advances in medical and pharmaceutical research, many common microbes and viruses that cause respiratory system infections have become resistant to common treatments. In this regard, the positive effects of medicinal plants used in traditional Iranian medicine in reducing symptoms and treating respiratory system infections in animals and humans have been reported. In this review, searching national and international databases using keywords such as medicinal plants, antiviral, immune system modulator, anti-inflammatory, antimicrobial, antioxidant, shortness of breath, expectorant and antitussives for studies published until 2022. In this review, the published studies related to medicinal plants used in Iranian traditional medicine, which have laboratory and clinical information in the direction of treating and improving the symptoms of respiratory tract infections, were investigated. The results showed that in traditional medicine, a large number of medicinal plants are used to treat infection and symptoms of respiratory diseases. Among them, Drimia maritima, Adiantum capillus-veneris, Glycyrrhiza glabra, Malva sylvestris, Cordia Myxa, Origanum vulgare, Artemisia absinthium, Hyssopus officinalis, Stachys schtschegleevii, Withania Somnifera, Syzygium aromaticum, Artemisia annua, Alpinia officinarum, Echinacea angustifolia and Thymus vulgaris have been used the most as expectorant, improve shortness of breath, antitussives, anti-virus and immune system modulator. Most of the laboratory and clinical researches have been done on Echinacea angustifolia as an immune system modulator and then Glycyrrhiza glabra as an antiviral. The most medicinal products licensed for sale in Iran's pharmaceutical market are related to Echinacea angustifolia and Thymus vulgaris for treatment of respiratory infections. It seems that the investigated medicinal plants have the ability to be investigated as a research platform to identify medicinal plants in supportive treatment to prevent and control the symptoms of respiratory infections. | ||
کلیدواژهها [English] | ||
Antitussives, Anti-virus, Expectorant, Medicinal plants, Shortness of breath | ||
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