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مروری بر ترکیبات فیتوشیمیایی و اثرات فیتوفارماکولوژیکی گیاه دارویی جاشیر(Prangos ferulacea) | ||
| پژوهش های پیشرفته در گیاهان دارویی | ||
| دوره 1، شماره 1، دی 1401، صفحه 25-35 اصل مقاله (1010.42 K) | ||
| نوع مقاله: مقاله مروری | ||
| شناسه دیجیتال (DOI): 10.30479/armp.2023.17818.1003 | ||
| نویسندگان | ||
| میر بابک بهادری1؛ حسین عبدالله نژاد2؛ آرش خرمی* 1 | ||
| 1استادیار، مرکز تحقیقات گیاهان دارویی، دانشکده علوم پزشکی مراغه، مراغه | ||
| 2دانش آموخته داروسازی، دانشکده داروسازی، دانشگاه علوم پزشکی ارومیه، ارومیه | ||
| تاریخ دریافت: 12 مهر 1401، تاریخ بازنگری: 06 دی 1401، تاریخ پذیرش: 18 دی 1401 | ||
| چکیده | ||
| جاشیر با نام علمی Prangos ferulacea جزو گیاهان دارویی شناخته شده و پرمصرف در نقاط گوناگون بویژه جنوب ایران و هم‌چنین کشورهای خاورمیانه و مدیترانه است که در طب سنتی برای درمان اختلالات گوارشی، اختلالات عصبی و درمان سرفه استفاده می‌شود. در این مطالعه به خواص فیتوشیمیایی و نیز اثرات فارماکولوژیک این گیاه پرداخته شده است. این مطالعه برای جمع‌بندی اطلاعات گیاه‌شناسی، فیتوشیمیایی، فارماکولوژیکی و تغذیه‌ای گیاه جاشیر به مرور منابع پرداخته، و نتایج مطالعات مختلف، گردآوری، جمع‌بندی و با یکدیگر مقایسه شده است. نتایج نشان داد این گونه دارویی ترکیبات طبیعی ارزشمندی چون کومارین‌ها، فلاونوئیدها، گلیکوزیدهای آنها و ترپنوئیدهای اسانسی دارد. طی بررسی مطالعات، مشخص شد گیاه جاشیر اثرات دارویی متعددی همچون آنتی‌اکسیدان، ضدمیکروب، ضد درد، ضد اسپاسم، و ضد دیابت دارد که در مطالعات برون‌تنی و حیوانی به اثبات رسیده است. نتایج این تحقیق می‌تواند مورد استفاده متخصصین شیمی گیاهی، فارماکولوژی و بالینی قرار گیرد. | ||
| کلیدواژه‌ها | ||
| اسانس؛ فلاونوئید؛ فیتوفارماکولوژی؛ فیتومدیسین؛ کومارین | ||
| عنوان مقاله [English] | ||
| A review on phytochemical components and phytopharmacological properties of Prangos ferulacea | ||
| نویسندگان [English] | ||
| Mir Babak Bahadori1؛ Hossein Abdollahnejad2؛ Arash Khorrami1 | ||
| 1Assistant Professor, Medicinal Plants Research Center, Maragheh University of Medical Sciences, Maragheh, Iran | ||
| 2Pharmacy Graduate, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran | ||
| چکیده [English] | ||
| Prangos ferulacea (Jashir) is one of the most popular herbs in Iran, Mediterranean, and Middle East countries which is traditionally used for several medicinal purposes such as digestive disorders, neurological disorders and cough. Present study is a review on phytochemical components and phytopharmacological properties of Prangos ferulacea. This study reviews the taxonomical, phytochemical, and phytopharmacological properties of Jashir. The results of conducted studies were achieved, evaluated and compared with each others. Results indicated that P. ferulacea contains natural bioactive products such as coumarins, flavonoids, their glycosides, and volatile terpenoids from essential oils. Moreover, in vitro and in vivo studies showed that P. ferulacea has important medicinal effects including antioxidant, antimicrobial, pain killer, anti-spasmodic, and antidiabetic activities. Results of this work could shed light on future phytochemical, pharmacological, and also clinical studies based on P. ferulacea formulations. | ||
| کلیدواژه‌ها [English] | ||
| Coumarin, Essential oil, Flavonoid, Phytomedicine, Phytopharmacology | ||
| مراجع | ||
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