اخبار و اعلانات
آمار
| تعداد نشریات | 19 |
| تعداد شماره‌ها | 380 |
| تعداد مقالات | 3,121 |
| تعداد مشاهده مقاله | 4,250,784 |
| تعداد دریافت فایل اصل مقاله | 2,844,966 |
مروری بر ترکیبات فیتوشیمیایی و اثرات فیتوفارماکولوژیکی گیاه دارویی جاشیر(Prangos ferulacea) | ||
| پژوهش های پیشرفته در گیاهان دارویی | ||
| دوره 1، شماره 1، دی 1401، صفحه 25-35 اصل مقاله (1010.42 K) | ||
| نوع مقاله: مقاله مروری | ||
| شناسه دیجیتال (DOI): 10.30479/armp.2023.17818.1003 | ||
| نویسندگان | ||
| میر بابک بهادری1؛ حسین عبدالله نژاد2؛ آرش خرمی* 1 | ||
| 1استادیار، مرکز تحقیقات گیاهان دارویی، دانشکده علوم پزشکی مراغه، مراغه | ||
| 2دانش آموخته داروسازی، دانشکده داروسازی، دانشگاه علوم پزشکی ارومیه، ارومیه | ||
| تاریخ دریافت: 12 مهر 1401، تاریخ بازنگری: 06 دی 1401، تاریخ پذیرش: 18 دی 1401 | ||
| چکیده | ||
| جاشیر با نام علمی Prangos ferulacea جزو گیاهان دارویی شناخته شده و پرمصرف در نقاط گوناگون بویژه جنوب ایران و هم‌چنین کشورهای خاورمیانه و مدیترانه است که در طب سنتی برای درمان اختلالات گوارشی، اختلالات عصبی و درمان سرفه استفاده می‌شود. در این مطالعه به خواص فیتوشیمیایی و نیز اثرات فارماکولوژیک این گیاه پرداخته شده است. این مطالعه برای جمع‌بندی اطلاعات گیاه‌شناسی، فیتوشیمیایی، فارماکولوژیکی و تغذیه‌ای گیاه جاشیر به مرور منابع پرداخته، و نتایج مطالعات مختلف، گردآوری، جمع‌بندی و با یکدیگر مقایسه شده است. نتایج نشان داد این گونه دارویی ترکیبات طبیعی ارزشمندی چون کومارین‌ها، فلاونوئیدها، گلیکوزیدهای آنها و ترپنوئیدهای اسانسی دارد. طی بررسی مطالعات، مشخص شد گیاه جاشیر اثرات دارویی متعددی همچون آنتی‌اکسیدان، ضدمیکروب، ضد درد، ضد اسپاسم، و ضد دیابت دارد که در مطالعات برون‌تنی و حیوانی به اثبات رسیده است. نتایج این تحقیق می‌تواند مورد استفاده متخصصین شیمی گیاهی، فارماکولوژی و بالینی قرار گیرد. | ||
| کلیدواژه‌ها | ||
| اسانس؛ فلاونوئید؛ فیتوفارماکولوژی؛ فیتومدیسین؛ کومارین | ||
| عنوان مقاله [English] | ||
| A review on phytochemical components and phytopharmacological properties of Prangos ferulacea | ||
| نویسندگان [English] | ||
| Mir Babak Bahadori1؛ Hossein Abdollahnejad2؛ Arash Khorrami1 | ||
| 1Assistant Professor, Medicinal Plants Research Center, Maragheh University of Medical Sciences, Maragheh, Iran | ||
| 2Pharmacy Graduate, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran | ||
| چکیده [English] | ||
| Prangos ferulacea (Jashir) is one of the most popular herbs in Iran, Mediterranean, and Middle East countries which is traditionally used for several medicinal purposes such as digestive disorders, neurological disorders and cough. Present study is a review on phytochemical components and phytopharmacological properties of Prangos ferulacea. This study reviews the taxonomical, phytochemical, and phytopharmacological properties of Jashir. The results of conducted studies were achieved, evaluated and compared with each others. Results indicated that P. ferulacea contains natural bioactive products such as coumarins, flavonoids, their glycosides, and volatile terpenoids from essential oils. Moreover, in vitro and in vivo studies showed that P. ferulacea has important medicinal effects including antioxidant, antimicrobial, pain killer, anti-spasmodic, and antidiabetic activities. Results of this work could shed light on future phytochemical, pharmacological, and also clinical studies based on P. ferulacea formulations. | ||
| کلیدواژه‌ها [English] | ||
| Coumarin, Essential oil, Flavonoid, Phytomedicine, Phytopharmacology | ||
| مراجع | ||
|
Abyshev A, Denisenko P, Kostyuchenko N, Ermakov A, Sheinker YN. 1972. Gosferol—A new furocoumarin from the roots of Prangos ferulacea. Chemistry of Natural Compounds 8 (1): 43-47. Abyshev A. 1968. Coumarins from the fruit of Prangos ferulacea. Chemistry of Natural Compounds 4 (2): 112-112. Akbari M, Esmaeili A, Zarea A, Saad N, Bagheri F. 2010. Chemical composition and antibacterial activity of essential oil from leaves, stems and flowers of Prangos ferulacea (L.) Lindl. grown in Iran. Bulgarian Chemical Communications 42 (1): 36-39. Aldemir R, Bingöl NT, Karsli MA, Akca I. 2015. Determination of nutrient content and digestibility characteristics of Prangos ferulacea (L.) on grazing lands of Eastern Anatolia. Turkish Journal of Veterinary and Animal Sciences 39 (2): 181-185. Amiri H. 2007. Chemical Composition and Antibacterial Activity of Essential Oil of Prangos ferulacea (L.) Lindl. Journal of Medicinal Plants 1 (21): 36-41. Bahadori MB, Zengin G, Bahadori S, Maggi F, Dinparast L. 2017. Chemical composition of essential oil, antioxidant, antidiabetic, anti-obesity, and neuroprotective properties of Prangos gaubae. Natural Product Communications 12 (12): 1945-1948. Baser K, Ermin N, Adigüzel N, Aytac Z. 1996. Composition of the essential oil of Prangos ferulacea (L.) Lindl. Journal of Essential Oil Research 8 (3): 297-298. Coruh N, Celep AS, Özgökçe F. 2007. Antioxidant properties of Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. and Heracleum persicum Desf. from Apiaceae family used as food in Eastern Anatolia and their inhibitory effects on glutathione-S-transferase. Food Chemistry 100 (3): 1237-1242. Coşkun B, Gülşen N, Umucalılar H. 2004. The nutritive value of Prangos ferulacea. Grass and Forage Science 59 (1): 15-19. Damyeh MS, Niakousari M. 2016. Impact of ohmic-assisted hydrodistillation on kinetics data, physicochemical and biological properties of Prangos ferulacea Lindle. essential oil: Comparison with conventional hydrodistillation. Innovative Food Science & Emerging Technologies 33: 387-396. Delnavazi M-R, Soleimani M, Hadjiakhoondi A, Yass N. 2017. Isolation of phenolic derivatives and essential oil analysis of Prangos ferulacea (L.) Lindl. aerial parts. Iranian Journal of Pharmaceutical Research 16 (Suppl): 207-215. Durmaz H, Sagun E, Tarakci Z, Ozgokce F. 2006. Antibacterial activities of Allium vineale, Chaerophyllum macropodum and Prangos ferulacea. African Journal of Biotechnology 5 (19): 1796-1798. Emamghoreishi M, Taghavi A, Javidnia K. 2012. The effect of aqueous and methanolic extracts of Prangos ferulacea on formalin-induced pain in mice. Journal of Jahrom University of Medical Sciences 9 (4): 2-7. Eshbakova K, Saidkhodzhaev A, Baser KH, Duman H, Vdovin A, Abdullaev N. 2006. Furocoumarins from Prangos ferulacea. Chemistry of Natural Compounds 42 (1): 102-103. Gholivand MB, Yamini Y, Dayeni M, Shokoohinia Y. 2015. The influence of the extraction mode on three coumarin compounds yield from Prangos ferulacea (L.) Lindl roots. Journal of the Iranian Chemical Society 12 (4): 707-714. Kafash NF, Farokhi F, Tukmacki A, Soltani KB. 2012. Hydro-alcoholic extract of the root of Prangos ferulacea (L.) Lindl can improve serum glucose and lipids in alloxan-induced diabetic rats. Avicenna Journal of Phytomedicine 2 (4): 179-187. Kuznetsova G, Abyshev A, Perel’son M, Sheinker YN, Pek GY. 1966. A new coumarin, pranferol, from the roots of Prangos ferulacea. Chemistry of Natural Compounds 2 (5): 252-255. Kuznetsova G, Abyshev A. 1965. Coumarins and furanocoumarins from the roots of Prangos ferulacea. Rastitel’nye Resursy 1: 221-224. Mehregan SESI. 2003. Chemical composition of the essential oil of Prangos asperula Boiss. Subsp. haussknechtii (Boiss.) Herrnst. Etheyn fruits. DARU Journal of Pharmaceutical Sciences 11 (2): 79-81. Mokhtari M, Mohammadi J. 2012. The effect of hydroalcoholic extracts of Prangos ferulacea on blood factors of kidney and liver functions in diabetic male wistar rats. Journal of Fasa University of Medical Sciences 2 (3): 174-180. Musa Özcan M, Dursun N, Arslan D. 2007. Some nutritional properties of Prangos ferulacea (L.) Lindl and Rheum ribes L. stems growing wild in Turkey. International Journal of Food Sciences and Nutrition 58 (2): 162-167. Razavi SM. 2012. Chemical composition and some allelopathic aspects of essential oils of (Prangos ferulacea L.) Lindl at different stages of growth. Journal of Agricultural Science and Technology 14: 349-356. Razavi SM, Zahri S, Zarrini G, Nazemiyeh H, Mohammadi S. 2009. Biological activity of quercetin-3-O-glucoside, a known plant flavonoid. Russian Journal of Bioorganic Chemistry 35 (3): 376-378. Razavi SM. 2012. Phenolic compounds from the aerial parts of Prangos ferulaceae, with antioxidant activity. EurAsian Journal of BioSciences 6: 91-96. Sadraei H, Shokoohinia Y, Sajjadi S, Ghadirian B. 2012. Antispasmodic effect of osthole and Prangos ferulacea extract on rat uterus smooth muscle motility. Research in Pharmaceutical Sciences 7 (3): 141-144. Sadraei H, Shokoohinia Y, Sajjadi S, Mozafari M. 2013. Antispasmodic effects of Prangos ferulacea acetone extract and its main component osthole on ileum contraction. Research in Pharmaceutical Sciences 8 (2): 137-144. Sajjadi SE, Shokoohinia Y, Gholamzadeh S. 2011. Chemical composition of essential oil of Prangos ferulacea (L.) Lindl. roots. Chemija 22 (3): 178-180. Seyed MR, Saber Z, Gholamreza Z, Hossein N, Sariyeh M. 2009. Biological activity of quercetin-3-o-glucoside, a known plant flavonoid. Russian Journal of Bioorganic Chemistry 35 (3): 414-416. Shokoohinia Y, Sajjadi S-E, Gholamzadeh S, Fattahi A, Behbahani M. 2014. Antiviral and cytotoxic evaluation of coumarins from Prangos ferulacea. Pharmaceutical Biology 52 (12): 1543-1549. Taherkhani M, Rustaiyan A, Masoudi S. 2012. Volatile constituents of the aerial parts of Ferulago subvelutina Rech. f., Ferulago stellata Boiss., leaves and flowers of Prangos ferulacea (L.) Lindle. and leaves of Ferula ovina (Boiss.) Boiss.: four Umbelliferae herbs from Iran. Asian Journal of Chemistry 24 (4): 1601-1606. | ||
|
آمار تعداد مشاهده مقاله: 509 تعداد دریافت فایل اصل مقاله: 441 |
||